Ontology highlight
ABSTRACT:
SUBMITTER: Zhao L
PROVIDER: S-EPMC6108125 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Zhao Lingfei L Hu Chenxia C Zhang Ping P Jiang Hua H Chen Jianghua J
Stem cell research & therapy 20180823 1
Acute kidney injury (AKI) remains a worldwide public health issue due to its increasing incidence, significant mortality, and lack of specific target-orientated therapy. Developments in mesenchymal stem cell (MSC) research make MSCs a promising candidate for AKI management but relevant clinical trials show confusing results (NCT00733876, NCT01602328). One primary cause of the limited therapeutic effect may result from poor engraftment of transplanted cells. To solve this problem, investigators h ...[more]