Ontology highlight
ABSTRACT:
SUBMITTER: Hellmann J
PROVIDER: S-EPMC6109422 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Hellmann Jason J Sansbury Brian E BE Wong Blenda B Li Xiaofeng X Singh Mansher M Nuutila Kristo K Chiang Nan N Eriksson Elof E Serhan Charles N CN Spite Matthew M
The Journal of investigative dermatology 20180317 9
Cutaneous injury causes underlying tissue damage that must be quickly repaired to minimize exposure to pathogens and to restore barrier function. While the role of growth factors in tissue repair is established, the role of lipid mediators in skin repair has not been investigated extensively. Using a mass spectrometry-based lipid mediator metabolomics approach, we identified D-series resolvins and related pro-resolving lipid mediators during skin injury in mice and pigs. Differentiation of human ...[more]