Ontology highlight
ABSTRACT:
SUBMITTER: Cho YA
PROVIDER: S-EPMC6110797 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Cho Young Ae YA Lee Jeonghee J Oh Jae Hwan JH Chang Hee Jin HJ Sohn Dae Kyung DK Shin Aesun A Kim Jeongseon J
Scientific reports 20180827 1
Based on an inverse association between vitamin D levels and the risks of colorectal diseases, a functional start codon polymorphism in the vitamin D receptor (VDR) gene is speculated to affect the risks for these diseases. To validate this hypothesis, we first conducted a case-control study of 695 colorectal cancer patients and 1,397 controls. The association of VDR FokI polymorphism with colorectal cancer risk was analyzed using a logistic regression model. In the present case-control study, c ...[more]