Ontology highlight
ABSTRACT:
SUBMITTER: Patton MG
PROVIDER: S-EPMC6111082 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Cell stress & chaperones 20180411 5
This work investigated the effect of a 6-day heat acclimation (HA) protocol on myotube metabolic responses at baseline and in response to a subsequent lipopolysaccharide (LPS) challenge. C2C12 myotubes were incubated for 2 h/day at 40 °C for 6 days (HA) or maintained at 37 °C (C). Following 24-h recovery, myotubes were challenged with 500 ng/ml LPS for 2 h, then collected for analysis of protein markers of mitochondrial biogenesis and macronutrient storage. Functional significance of these chang ...[more]