Ontology highlight
ABSTRACT:
SUBMITTER: Maslyk M
PROVIDER: S-EPMC6111191 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Masłyk Maciej M Janeczko Monika M Demchuk Oleg M OM Boguszewska-Czubara Anna A Golczyk Hieronim H Sierosławska Anna A Rymuszka Anna A Martyna Aleksandra A Kubiński Konrad K
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 20171205 2
In this study, we applied various assays to reveal new activities of phenylcyanomethylenequinone oxime-4-(hydroxyimino) cyclohexa-2,5-dien-1-ylidene](phenyl)ethanenitrile (<b>4-AN</b>) for potential anti-microbial applications. These assays demonstrated (a) the antimicrobial effect on bacterial and fungal cultures, (b) the effect on the <i>in vitro</i> activity of the kinase CK2, (c) toxicity towards human erythrocytes, the Caco-2 cancer cell line, and embryonic development of Zebrafish. We demo ...[more]