Ontology highlight
ABSTRACT:
SUBMITTER: Huang J
PROVIDER: S-EPMC6112310 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Genomics, proteomics & bioinformatics 20180427 2
More than 100 types of chemical modifications in RNA have been well documented. Recently, several modifications, such as N<sup>6</sup>-methyladenosine (m<sup>6</sup>A), have been detected in mRNA, opening the window into the realm of epitranscriptomics. The m<sup>6</sup>A modification is the most abundant modification in mRNA and non-coding RNA (ncRNA). At the molecular level, m<sup>6</sup>A affects almost all aspects of mRNA metabolism, including splicing, translation, and stability, as well as ...[more]