Ontology highlight
ABSTRACT:
SUBMITTER: Zhou Y
PROVIDER: S-EPMC6117325 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Zhou Yuzhen Y Chu Li L Wang Qi Q Dai Weixing W Zhang Xiaozhou X Chen Jianfeng J Li Ling L Ding Peipei P Zhang Long L Gu Hongyu H Li Luying L Lv Xinyue X Zhang Wei W Zhou Danlei D Zhang Pingzhao P Cai Guoxiang G Zhao Kuaile K Hu Weiguo W
Cell death & disease 20180830 9
Radiation therapy is an important treatment modality for esophageal cancer. However, acquisition of radioresistance ultimately results in esophageal cancer relapse. CD59, a membrane-bound complement regulatory protein, can transduce signals via a Src kinase in the lipid raft, thus playing a complement-independent role. However, the effect of CD59 on the esophageal cancer response to ionizing radiation remains unclear. In this study, we found that the expression level of CD59 was positively corre ...[more]