Ontology highlight
ABSTRACT:
SUBMITTER: Sevvana M
PROVIDER: S-EPMC6125166 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Sevvana Madhumati M Long Feng F Miller Andrew S AS Klose Thomas T Buda Geeta G Sun Lei L Kuhn Richard J RJ Rossmann Michael G MG
Structure (London, England : 1993) 20180626 9
Among the several arthropod-borne human flaviviral diseases, the recent outbreak of Zika virus (ZIKV) has caused devastating birth defects and neurological disorders, challenging the world with another major public health concern. We report here the refined structure of the mature ZIKV at a resolution of 3.1 Å as determined by cryo-electron microscopic single-particle reconstruction. The improvement in the resolution, compared with previous enveloped virus structures, was the result of optimized ...[more]