Ontology highlight
ABSTRACT:
SUBMITTER: Feng W
PROVIDER: S-EPMC6126332 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Feng Wanjing W Liu Xin X Zhao Xiaoying X Huang Mingzhu M Guo Weijian W Yin Jiliang J Chen Zhiyu Z Zhu Xiaodong X
Oncology letters 20180716 4
Cytochrome-P450 enzymes, ATP-binding cassette transporters, and solute carriers mediate drug metabolism as metabolic enzymes and membrane transporters, respectively. The present study investigated whether single nucleotide polymorphisms (SNPs) in genes encoding these proteins were predictive or prognostic factors in patients with metastatic gastric cancer (MGC) undergoing chemotherapy. A retrospective study of 108 MGC patients who received epirubicin, oxaliplatin, and 5-fluorouracil (EOF) as fir ...[more]