Screening for candidate genes related with histological microstructure, meat quality and carcass characteristic in pig based on RNA-seq data.

ABSTRACT:

Objective

The aim of the present study was to identify genetic variants based on RNA-seq data, obtained via transcriptome sequencing of muscle tissue of pigs differing in muscle histological structure, and to verify the variants' effect on histological microstructure and production traits in a larger pig population.

Methods

RNA-seq data was used to identify the panel of single nucleotide polymorphisms (SNPs) significantly related with percentage and diameter of each fiber type (I, IIA, IIB). Detected polymorphisms were mapped to quantitative trait loci (QTLs) regions. Next, the association study was performed on 944 animals representing five breeds (Landrace, Large White, Pietrain, Duroc, and native Puławska breed) in order to evaluate the relationship of selected SNPs and h

SUBMITTER: Ropka-Molik K 

PROVIDER: S-EPMC6127584 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature