Unknown

Dataset Information

0

Progressive fuzzy cation-? assembly of biological catecholamines.


ABSTRACT: Biological functions depend on biomolecular assembly processes. Assemblies of lipid bilayers, actins, microtubules, or chromosomes are indispensable for cellular functions. These hierarchical assembly processes are reasonably predictable by understanding chemical structures of the defined building blocks and their interactions. However, biopigment assembly is rather fuzzy and unpredictable because a series of covalently coupled intermediates from catecholamine oxidation pathways progressively form a higher-level hierarchy. This study reports a different yet unexplored type of assembly process named "cation-? progressive assembly." We demonstrated for the first time that the cation-? is the primary mechanism for intermolecular assembly in dopamine-melanin biopigment. We also found that the self-assembled products physically grow and chemically gain new functions "progressively" over time in which cation-? plays important roles. The progressive assembly explains how biological systems produce wide spectra of pigment colors and broad wavelength absorption through energy-efficient processes. Furthermore, we also demonstrate surface-independent wettability control using cation-? progressive assembly.

SUBMITTER: Hong S 

PROVIDER: S-EPMC6128673 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

altmetric image

Publications

Progressive fuzzy cation-π assembly of biological catecholamines.

Hong Seonki S   Wang Younseon Y   Park Sung Young SY   Lee Haeshin H  

Science advances 20180907 9


Biological functions depend on biomolecular assembly processes. Assemblies of lipid bilayers, actins, microtubules, or chromosomes are indispensable for cellular functions. These hierarchical assembly processes are reasonably predictable by understanding chemical structures of the defined building blocks and their interactions. However, biopigment assembly is rather fuzzy and unpredictable because a series of covalently coupled intermediates from catecholamine oxidation pathways progressively fo  ...[more]

Similar Datasets

| S-EPMC2673503 | biostudies-literature
| S-EPMC4603898 | biostudies-literature
| S-EPMC6336244 | biostudies-literature
| S-EPMC4766190 | biostudies-literature
| S-EPMC2277399 | biostudies-literature
| S-EPMC3247861 | biostudies-other
| S-EPMC2553328 | biostudies-other
| S-EPMC5456510 | biostudies-other
| S-EPMC6951296 | biostudies-literature
| S-EPMC8389894 | biostudies-literature