Ontology highlight
ABSTRACT:
SUBMITTER: Zhou CW
PROVIDER: S-EPMC6129524 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Zhou Cheng Wei CW Zhao Wei Jun WJ Zhu Yong Gang YG Zhao Xiao Dong XD
American journal of translational research 20180815 8
MicroRNA-185 (miR-185) is down-regulated in various tumor types. However, the cytological mechanism for inhibiting and restraining tumor growth of non-small-cell carcinoma (NSCLC) remains to be elucidated. In this study, it was revealed that miR-185 is significantly down-regulated in both NSCLC tumor tissues and cell lines, and over-expression of miR-185 inhibited cell growth, migration and invasion. To investigate the cellular machinery involved in miR-185's regulation of tumor growth, it was f ...[more]