Ontology highlight
ABSTRACT:
SUBMITTER: Haroon E
PROVIDER: S-EPMC6131242 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Haroon Ebrahim E Chen Xiangchuan X Li Zhihao Z Patel Thrusharth T Woolwine Bobbi J BJ Hu Xiaoping P XP Felger Jennifer C JC Miller Andrew H AH
Translational psychiatry 20180910 1
Combined increases in peripheral inflammation and brain glutamate may identify a subtype of depression with distinct neuroimaging signatures. Two contrasting subgroups of depressed subjects-with and without combined elevations in plasma C-reactive protein (CRP) and basal ganglia glutamate (high and low CRP-Glu, respectively) were identified by hierarchical clustering using plasma CRP (indexing peripheral inflammation) and magnetic resonance spectroscopy (MRS)-based measurement of left basal gang ...[more]