Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC6131487 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Wang Jialing J Yuan Shuai S Zhu Dongjie D Tang Hao H Wang Nan N Chen Wenyuan W Gao Qiang Q Li Yuhua Y Wang Junzhi J Liu Hongrong H Zhang Xinzheng X Rao Zihe Z Wang Xiangxi X
Nature communications 20180910 1
Herpes simplex viruses (HSVs) cause human oral and genital ulcer diseases. Patients with HSV-2 have a higher risk of acquiring a human immunodeficiency virus infection. HSV-2 is a member of the α-herpesvirinae subfamily that together with the β- and γ-herpesvirinae subfamilies forms the Herpesviridae family. Here, we report the cryo-electron microscopy structure of the HSV-2 C-capsid with capsid-vertex-specific component (CVSC) that was determined at 3.75 Å using a block-based reconstruction str ...[more]