Ontology highlight
ABSTRACT:
SUBMITTER: Ng SS
PROVIDER: S-EPMC6131727 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Ng Soon Seng SS Saeb-Parsy Kourosh K Blackford Samuel J I SJI Segal Joe M JM Serra Maria Paola MP Horcas-Lopez Marta M No Da Yoon DY Mastoridis Sotiris S Jassem Wayel W Frank Curtis W CW Cho Nam Joon NJ Nakauchi Hiromitsu H Glenn Jeffrey S JS Rashid S Tamir ST
Biomaterials 20180727
Generation of human organoids from induced pluripotent stem cells (iPSCs) offers exciting possibilities for developmental biology, disease modelling and cell therapy. Significant advances towards those goals have been hampered by dependence on animal derived matrices (e.g. Matrigel), immortalized cell lines and resultant structures that are difficult to control or scale. To address these challenges, we aimed to develop a fully defined liver organoid platform using inverted colloid crystal (ICC) ...[more]