Ontology highlight
ABSTRACT:
SUBMITTER: Seo GY
PROVIDER: S-EPMC6132068 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Seo Goo-Young GY Shui Jr-Wen JW Takahashi Daisuke D Song Christina C Wang Qingyang Q Kim Kenneth K Mikulski Zbigniew Z Chandra Shilpi S Giles Daniel A DA Zahner Sonja S Kim Pyeung-Hyeun PH Cheroutre Hilde H Colonna Marco M Kronenberg Mitchell M
Cell host & microbe 20180801 2
Innate lymphoid cells (ILCs) are important regulators of early infection at mucosal barriers. ILCs are divided into three groups based on expression profiles, and are activated by cytokines and neuropeptides. Yet, it remains unknown if ILCs integrate other signals in providing protection. We show that signaling through herpes virus entry mediator (HVEM), a member of the tumor necrosis factor (TNF) receptor superfamily, in ILC3 is important for host defense against oral infection with the bacteri ...[more]