The association between brain volume, cortical brain infarcts, and physical frailty.
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ABSTRACT:
SUBMITTER: Kant IMJ
PROVIDER: S-EPMC6135646 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
The association between brain volume, cortical brain infarcts, and physical frailty.
Kant Ilse M J IMJ de Bresser Jeroen J van Montfort Simone J T SJT Aarts Ellen E Verlaan Jorrit-Jan JJ Zacharias Norman N Winterer Georg G Spies Claudia C Slooter Arjen J C AJC Hendrikse Jeroen J
Neurobiology of aging 20180630
Physical frailty is an age-associated syndrome of decreased reserve leading to vulnerability to physiological stressors and associated with negative outcomes. The underlying structural brain abnormalities of physical frailty are unclear. We investigated the association between brain volume, cortical brain infarcts, and physical frailty. In this multicenter study, 214 nondemented participants were classified as frail (n = 32), prefrail (n = 107), or nonfrail (n = 75) based on the Fried frailty ph ...[more]
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