Non-inverted pedicle internal limiting membrane transposition for large macular holes.

ABSTRACT: PURPOSE:The purpose of this study is to investigate the effectiveness of a new surgical technique of non-inverted pedicle internal limiting membrane (ILM) transposition for the treatment of eyes with large macular hole. METHODS:This is a retrospective, consecutive, interventional case series. Twelve eyes of 12 consecutive patients who underwent vitrectomy for the treatment of a large macular hole (MH size?>?400?µm) were treated. ILM was peeled and left with a pedicle attached to the superior temporal retina. The macular hole was covered by transposition of the pedicle ILM in a non-inverted way. Preoperative and postoperative best-corrected visual acuity (BCVA), SD-OCT image, macular sensitivity by microperimetry, and multifocal electroretinogram (mERG) response were evaluated. All of the patients were followed for more than 3 months. RESULTS:Postoperative OCT examination confirmed 11 of 12 macular hole closed (91.7%). Six macular hole filled with silicone oil closed as early as the next day. The postoperative BCVA significantly increased compared with preoperative BCVA (P?=?0.002). The improvement of macular sensitivity within 2° and 8° circle was also statistical significant (P?=?0.018 and P?=?0.017, respectively). Fixation stability, shown as the percentage of fixation point within the 2° circle and 4° circle, was remarkably improved (P?=?0.017 and P?=?0.018, respectively). The R1/R2 and R1/R4 ring ratios also increased significantly as compared with that of baseline. CONCLUSION:These findings indicate that the non-inverted pedicle ILM transposition results in a high incidence of anatomic closure with good visual outcome for the treatment of large macular hole.

SUBMITTER: Hu Z 

PROVIDER: S-EPMC6137144 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature