Ontology highlight
ABSTRACT:
SUBMITTER: Ramirez-Vargas G
PROVIDER: S-EPMC6141592 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Ramírez-Vargas Gabriel G López-Ureña Diana D Badilla Adriana A Orozco-Aguilar Josué J Murillo Tatiana T Rojas Priscilla P Riedel Thomas T Overmann Jörg J González Gabriel G Chaves-Olarte Esteban E Quesada-Gómez Carlos C Rodríguez César C
Scientific reports 20180917 1
The population structure of Clostridium difficile currently comprises eight major genomic clades. For the highly divergent C-I clade, only two toxigenic strains have been reported, which lack the tcdA and tcdC genes and carry a complete locus for the binary toxin (CDT) next to an atypical TcdB monotoxin pathogenicity locus (PaLoc). As part of a routine surveillance of C. difficile in stool samples from diarrheic human patients, we discovered three isolates that consistently gave negative results ...[more]