Ontology highlight
ABSTRACT:
SUBMITTER: Saunders J
PROVIDER: S-EPMC6143791 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Saunders Jessica J Hore Zoe Z Gentry Clive C McMahon Stephen S Denk Franziska F
Frontiers in molecular neuroscience 20180912
Traditionally, neuroscience has had to rely on mixed tissue analysis to examine transcriptional and epigenetic changes in the context of nervous system function or pathology. However, particularly when studying chronic pain conditions, this approach can be flawed, since it neglects to take into account the shifting contribution of different cell types across experimental conditions. Here, we demonstrate this using the example of DNA methyltransferases (DNMTs) - a group of epigenetic modifiers co ...[more]