Ontology highlight
ABSTRACT:
SUBMITTER: Apkarian AV
PROVIDER: S-EPMC4858177 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Apkarian A Vania AV Mutso Amelia A AA Centeno Maria V MV Kan Lixin L Wu Melody M Levinstein Marjorie M Banisadr Ghazal G Gobeske Kevin T KT Miller Richard J RJ Radulovic Jelena J Hen René R Kessler John A JA
Pain 20160201 2
The full role of adult hippocampal neurogenesis (AHN) remains to be determined, yet it is implicated in learning and emotional functions, and is disrupted in negative mood disorders. Recent evidence indicates that AHN is decreased in persistent pain consistent with the idea that chronic pain is a major stressor, associated with negative moods and abnormal memories. Yet, the role of AHN in development of persistent pain has remained unexplored. In this study, we test the influence of AHN in posti ...[more]