Ontology highlight
ABSTRACT:
SUBMITTER: Keebaugh ES
PROVIDER: S-EPMC6146667 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Keebaugh Erin S ES Yamada Ryuichi R Obadia Benjamin B Ludington William B WB Ja William W WW
iScience 20180608
In Drosophila, microbial association can promote development or extend life. We tested the impact of microbial association during malnutrition and show that microbial quantity is a predictor of fly longevity. Although all tested microbes, when abundantly provided, can rescue lifespan on low-protein diet, the effect of a single inoculation seems linked to the ability of that microbial strain to thrive under experimental conditions. Microbes, dead or alive, phenocopy dietary protein, and the calcu ...[more]