Ontology highlight
ABSTRACT:
SUBMITTER: Lin HA
PROVIDER: S-EPMC6148063 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Lin Hsiao-Chun Amy HA Déan-Ben Xosé Luís XL Reiss Michael M Schöttle Verena V Wahl-Schott Christian A CA Efimov Igor R IR Razansky Daniel D
Scientific reports 20180920 1
The Langendorff-perfused heart technique has become the model of choice for multiparametric optical mapping of cardiac function and electrophysiology. However, photon scattering in tissues represents a significant drawback of the optical imaging approach, fundamentally limiting its mapping capacity to the heart surface. This work presents the first implementation of the optoacoustic approach for 4D imaging of the entire beating isolated mouse heart. The method combines optical excitation and aco ...[more]