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Four New Glycosides from the Rhizoma of Anemarrhena asphodeloides.

ABSTRACT: Four new compounds, aneglycoside A-C (1-3) and timosaponin U (4), were isolated from the rhizomes of Anemarrhena asphodeloides. Their structures were determined through extensive spectroscopic analysis, chemical characteristics, and high-resolution mass spectrometry (HRMS). All the isolations were evaluated for cytotoxicity against HepG2, Hela, and SGC7901 human cancer lines. Compounds 1, 2, and 4 showed weak antiproliferative activities on HepG2, Hela, and SGC7901 cells.

SUBMITTER: Yang BY

PROVIDER: S-EPMC6150167 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

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Four New Glycosides from the Rhizoma of Anemarrhena asphodeloides.

Yang Bing-You BY Bi Xue-Yan XY Liu Yan Y Li Guo-Yu GY Yin Xin X Kuang Hai-Xue HX

Molecules (Basel, Switzerland) 20171122 11

Four new compounds, aneglycoside A-C (1-3) and timosaponin U (4), were isolated from the rhizomes of Anemarrhena asphodeloides. Their structures were determined through extensive spectroscopic analysis, chemical characteristics, and high-resolution mass spectrometry (HRMS). All the isolations were evaluated for cytotoxicity against HepG2, Hela, and SGC7901 human cancer lines. Compounds 1, 2, and 4 showed weak antiproliferative activities on HepG2, ...[more]

PMID: 29165329

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