Dataset Information

Glucose regulation and physical performance among older people: the Helsinki Birth Cohort Study.

ABSTRACT: AIMS:To assess whether disturbances in glucose regulation are associated with impairment in physical performance during a 10-year follow-up. METHODS:475 Men and 603 women from the Helsinki Birth Cohort Study were studied. Glucose regulation was evaluated with a 2-h 75-g oral glucose tolerance test (OGTT) in 2001-2004. Subjects were categorised as having either impaired fasting glucose (IFG), impaired glucose tolerance (IGT), newly diagnosed diabetes or previously known diabetes. Physical performance was assessed approximately 10 years later using the validated senior fitness test (SFT). The relationship between glucose regulation and the overall SFT score was estimated using multiple linear regression models. RESULTS:The mean age was 70.8 years for men and 71.0 years for women when physical performance was assessed. The mean SFT score for the whole population was 45.0 (SD 17.5) points. The SFT score decreased gradually with increased impairment in glucose regulation. Individuals with previously known diabetes had the lowest overall SFT score in the fully adjusted model (mean difference compared to normoglycaemic individuals -?11.56 points, 95% CI - 16.15 to - 6.98, p?

SUBMITTER: Astrom MJ

PROVIDER: S-EPMC6150438 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Glucose regulation and physical performance among older people: the Helsinki Birth Cohort Study.

Åström Max J MJ von Bonsdorff Mikaela B MB Perälä Mia M MM Salonen Minna K MK Rantanen Taina T Kajantie Eero E Simonen Mika M Pohjolainen Pertti P Osmond Clive C Eriksson Johan G JG

Acta diabetologica 20180721 10

<h4>Aims</h4>To assess whether disturbances in glucose regulation are associated with impairment in physical performance during a 10-year follow-up.<h4>Methods</h4>475 Men and 603 women from the Helsinki Birth Cohort Study were studied. Glucose regulation was evaluated with a 2-h 75-g oral glucose tolerance test (OGTT) in 2001-2004. Subjects were categorised as having either impaired fasting glucose (IFG), impaired glucose tolerance (IGT), newly diagnosed diabetes or previously known diabetes. P ...[more]

PMID: 30032324

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Project description:Cross-sectional relationships between physical activity and health have been explored extensively, but less is known about how physical activity changes with time in older people. The aim of this study was to assess baseline predictors of how objectively measured physical activity changes with time in older people.Longitudinal cohort study using data from the Physical Activity Cohort Scotland. A sample of community-dwelling older people aged 65 and over were recruited in 2009-2011, then followed up 2-3 years later. Physical activity was measured using Stayhealthy RT3 accelerometers over 7 days. Other data collected included baseline comorbidity, health-related quality of life (SF-36), extended Theory of Planned Behaviour Questionnaire and Social Capital Module of the General Household Survey. Associations between follow-up accelerometer counts and baseline predictors were analysed using a series of linear regression models, adjusting for baseline activity levels and follow-up time.Follow up data were available for 339 of the original 584 participants. The mean age was 77 years, 185 (55%) were female and mean follow up time was 26 months. Mean activity counts fell by between 2% per year (age < =80, deprivation decile 5-10) and 12% per year (age > 80, deprivation decile 5-10) from baseline values. In univariate analysis age, sex, deprivation decile, most SF-36 domains, most measures of social connectedness, most measures from the extended Theory of Planned Behaviour, hypertension, diabetes mellitus, chronic pain and depression score were significantly associated with adjusted activity counts at follow-up. In multivariate regression age, satisfactory friend network, SF-36 physical function score, and the presence of diabetes mellitus were independent predictors of activity counts at follow up after adjustment for baseline count and duration of follow up.Health status and social connectedness, but not extended Theory of Planned Behaviour measures, independently predicted changes in physical activity in community dwelling older people.

Dataset Information

Glucose regulation and physical performance among older people: the Helsinki Birth Cohort Study.

Publications

Glucose regulation and physical performance among older people: the Helsinki Birth Cohort Study.

Similar Datasets

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