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RNA capping by mitochondrial and multi-subunit RNA polymerases.

ABSTRACT: Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP - containing cofactors. However, a functional role of universal RNAP - catalysed capping is not yet clear.

SUBMITTER: Julius C

PROVIDER: S-EPMC6150613 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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RNA capping by mitochondrial and multi-subunit RNA polymerases.

Julius Christina C Riaz-Bradley Amber A Yuzenkova Yulia Y

Transcription 20180425 5

Recently, it was found that bacterial and eukaryotic transcripts are capped with cellular cofactors installed by their respective RNA polymerases (RNAPs) during transcription initiation. We now show that mitochondrial RNAP efficiently caps transcripts with ADP - containing cofactors. However, a functional role of universal RNAP - catalysed capping is not yet clear. ...[more]

PMID: 29624107

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