A Systematic Review of Computational Drug Discovery, Development, and Repurposing for Ebola Virus Disease Treatment.
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ABSTRACT:
SUBMITTER: Schuler J
PROVIDER: S-EPMC6151658 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
A Systematic Review of Computational Drug Discovery, Development, and Repurposing for Ebola Virus Disease Treatment.
Schuler James J Hudson Matthew L ML Schwartz Diane D Samudrala Ram R
Molecules (Basel, Switzerland) 20171020 10
Ebola virus disease (EVD) is a deadly global public health threat, with no currently approved treatments. Traditional drug discovery and development is too expensive and inefficient to react quickly to the threat. We review published research studies that utilize computational approaches to find or develop drugs that target the Ebola virus and synthesize its results. A variety of hypothesized and/or novel treatments are reported to have potential anti-Ebola activity. Approaches that utilize mult ...[more]
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