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Effects of blood-flow restriction on biomarkers of myogenesis in response to resistance exercise.

ABSTRACT: We investigated the acute myogenic response to resistance exercise with and without blood-flow restriction (BFR). Six men and women (age, 22 ± 1 years) performed unilateral knee extensions at 40% of 1-repetition maximum with or without (CNTRL) BFR applied via pressure cuff inflated to 220 mm Hg. Muscle biopsies were collected at 4 h and 24 h postexercise. Addition of BFR increased myoD and c-Met messenger RNA expression relative to CNTRL. Expression of hepatocyte growth factor protein was significantly higher following CNTRL.

SUBMITTER: Layne AS 

PROVIDER: S-EPMC6151869 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature

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Effects of blood-flow restriction on biomarkers of myogenesis in response to resistance exercise.

Layne Andrew S AS   Larkin-Kaiser Kelly K   MacNeil R Gavin RG   Dirain Marvin M   Sandesara Bhanuprasad B   Manini Todd M TM   Buford Thomas W TW  

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20161018 1

We investigated the acute myogenic response to resistance exercise with and without blood-flow restriction (BFR). Six men and women (age, 22 ± 1 years) performed unilateral knee extensions at 40% of 1-repetition maximum with or without (CNTRL) BFR applied via pressure cuff inflated to 220 mm Hg. Muscle biopsies were collected at 4 h and 24 h postexercise. Addition of BFR increased myoD and c-Met messenger RNA expression relative to CNTRL. Expression of hepatocyte growth factor protein was signif  ...[more]

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