Ontology highlight
ABSTRACT:
SUBMITTER: Yao Z
PROVIDER: S-EPMC6153407 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20180718 8
The study of enzyme substrate specificity is vital for developing potential applications of enzymes. However, the routine experimental procedures require lot of resources in the discovery of novel substrates. This article reports an in silico structure-based algorithm called Crius, which predicts substrates for enzyme. The results of this fragment-based algorithm show good agreements between the simulated and experimental substrate specificities, using a lipase from Candida antarctica (CALB), a ...[more]