Ontology highlight
ABSTRACT:
SUBMITTER: Bai C
PROVIDER: S-EPMC6154594 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20170417 4
A cytotoxicity-guided phytochemical investigation of <i>Anemone vitifolia</i> roots led to the isolation of six oleanane saponins (<b>1</b>-<b>6</b>), which were reported from the species for the first time. Their structures were determined by comparing its MS and NMR data with those in literature. Compounds <b>1</b>-<b>4</b> showed significant inhibitory effects on the proliferation of hepatocellular carcinoma HepG2 cells with IC<sub>50</sub> values ranging from 2.0 to 8.5 μM, compared to posit ...[more]