Ontology highlight
ABSTRACT:
SUBMITTER: Xiong L
PROVIDER: S-EPMC6154706 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20170424 4
Enzymes involved in the coagulation process have received great attention as potential targets for the development of oral anti-coagulants. Among these enzymes, coagulation factor Xa (FXa) has remained the center of attention in the last decade. In this study, 16 ginsenosides and two sapogenins were isolated, identified and quantified. To determine the inhibitory potential on FXa, the chromogenic substrates method was used. The assay suggested that compounds <b>5</b>, <b>13</b> and <b>18</b> wer ...[more]