Ontology highlight
ABSTRACT:
SUBMITTER: Zhang J
PROVIDER: S-EPMC6155061 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Zhang Jian J Yang Jiarun J Han Dong D Zhao Xueyan X Ma Jingsong J Ban Bo B Zhu Xiongzhao X Yang Yanjie Y Cao Depin D Qiu Xiaohui X
Scientific reports 20180921 1
The purpose of this study is to explore Dvl3 variants and their interaction with negative life events on MDD susceptibility in a Chinese Han population. Additionally, we also attempted to identify whether there is an association between Dvl3 variants and pro-inflammatory cytokines. A total of 1102 participants, consisting of 550 patients with MDD and 552 healthy subjects, were recruited for genotyping by TaqMan allelic discrimination assay. Pro-inflammatory cytokine mRNA levels in peripheral blo ...[more]