Changes in the Intestine Microbial, Digestive, and Immune-Related Genes of Litopenaeus vannamei in Response to Dietary Probiotic Clostridium butyricum Supplementation.

ABSTRACT: The intestine barrier serves as the front-line defense in shrimp. Clostridium butyricum (CB) can produce butyric acid that provides energy for the intestine epithelial cells of the host. However, the effects of dietary CB on the intestine microbiome and the digestion and immunity of the host is not clear. In this study, we therefore investigated the composition and metabolic activity of the intestine microbiome, and digestive and immune-related gene expression in Litopenaeus vannamei fed with diets containing different levels of CB: basal diet (control), 2.5 × 10⁹ CFU kg^-1 diet (CB1), 5.0 × 10⁹ CFU kg^-1 diet (CB2), and 1.0 × 10¹⁰ CFU kg^-1 diet (CB3) for 56 days. Dietary CB altered the composition of the intesti

SUBMITTER: Duan Y 

PROVIDER: S-EPMC6156435 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature