Ontology highlight
ABSTRACT:
SUBMITTER: Justice AE
PROVIDER: S-EPMC6157130 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Justice Anne E AE Howard Annie Green AG Fernández-Rhodes Lindsay L Graff Misa M Tao Ran R North Kari E KE
BMC proceedings 20180917 Suppl 9
Even though there has been great success in identifying lipid-associated single-nucleotide polymorphisms (SNPs), the mechanisms through which the SNPs act on each trait are poorly understood. The emergence of large, complex biological data sets in well-characterized cohort studies offers an opportunity to investigate the genetic effects on trait variability as a way of informing the causal genes and biochemical pathways that are involved in lipoprotein metabolism. However, methods for simultaneo ...[more]