Ontology highlight
ABSTRACT:
SUBMITTER: Cantor R
PROVIDER: S-EPMC6157159 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Cantor Rita R Navarro Linda L Pan Calvin C
BMC proceedings 20180917 Suppl 9
As part of GAW20, we analyzed the familiality and variability of methylation to identify cytosine-phosphate-guanine (CpG) sites responsive to treatment with fenofibrate. Methylation was measured at approximately 450,000 sites in pedigree members, prior to and after 3 weeks of treatment. Initially, we aimed to identify responsive sites by analyzing the pre- and posttreatment methylation changes within individuals, but these data exhibited a confounding treatment/batch effect. We applied an altern ...[more]