Ontology highlight
ABSTRACT:
SUBMITTER: Gharat TP
PROVIDER: S-EPMC6158043 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Gharat Tanmay P TP Diaz-Rodriguez Patricia P Erndt-Marino Josh D JD Jimenez Vergara Andrea Carolina AC Munoz Pinto Dany J DJ Bearden Robert N RN Huggins Shannon S SS Grunlan Melissa M Saunders W Brian WB Hahn Mariah S MS
Journal of biomedical materials research. Part A 20180514 9
Tissue engineered bone grafts based on bone marrow mesenchymal stromal cells (MSCs) are being actively developed for craniomaxillofacial (CMF) applications. As for all tissue engineered implants, the bone-regenerating capacity of these MSC-based grafts must first be evaluated in animal models prior to human trials. Canine models have traditionally resulted in improved clinical translation of CMF grafts relative to other animal models. However, the utility of canine CMF models for evaluating MSC- ...[more]