Pathway-based analysis of genome-wide association study of circadian phenotypes.
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ABSTRACT:
SUBMITTER: Zhu DD
PROVIDER: S-EPMC6163116 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Publications
Pathway-based analysis of genome-wide association study of circadian phenotypes.
Zhu Di-di DD Yuan Jia-Min JM Zhu Rui R Wang Yao Y Qian Zhi-Yong ZY Zou Jian-Gang JG
Journal of biomedical research 20180901 5
Sleepiness affects normal social life, which attracts more and more attention. Circadian phenotypes contribute to obvious individual differences in susceptibility to sleepiness. We aimed to identify candidate single nucleotide polymorphisms (SNPs) which may cause circadian phenotypes, elucidate the potential mechanisms, and generate corresponding SNP-gene-pathways. A genome-wide association studies (GWAS) dataset of circadian phenotypes was utilized in the study. Then, the Identify Candidate Cau ...[more]
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