Chromosomal disorders: estimating baseline birth prevalence and pregnancy outcomes worldwide.
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ABSTRACT:
SUBMITTER: Moorthie S
PROVIDER: S-EPMC6167258 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
Chromosomal disorders: estimating baseline birth prevalence and pregnancy outcomes worldwide.
Moorthie Sowmiya S Blencowe Hannah H Darlison Matthew W MW Gibbons Stephen S Lawn Joy E JE Mastroiacovo Pierpaolo P Morris Joan K JK Modell Bernadette B
Journal of community genetics 20170926 4
Chromosomal disorders, of which Down syndrome is the most common, can cause multi-domain disability. In addition, compared to the general population, there is a higher frequency of death before the age of five. In many settings, large gaps in data availability have hampered policy-making, programme priorities and resource allocation for these important conditions. We have developed methods, which overcome this lack of data and allow estimation of the burden of affected pregnancies and their outc ...[more]
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