Unknown

Dataset Information

0

Menstrual cycle rhythmicity: metabolic patterns in healthy women.


ABSTRACT: The menstrual cycle is an essential life rhythm governed by interacting levels of progesterone, estradiol, follicular stimulating, and luteinizing hormones. To study metabolic changes, biofluids were collected at four timepoints in the menstrual cycle from 34 healthy, premenopausal women. Serum hormones, urinary luteinizing hormone and self-reported menstrual cycle timing were used for a 5-phase cycle classification. Plasma and urine were analyzed using LC-MS and GC-MS for metabolomics and lipidomics; serum for clinical chemistries; and plasma for B vitamins using HPLC-FLD. Of 397 metabolites and micronutrients tested, 208 were significantly (p?

SUBMITTER: Draper CF 

PROVIDER: S-EPMC6167362 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

altmetric image

Publications

Menstrual cycle rhythmicity: metabolic patterns in healthy women.

Draper C F CF   Duisters K K   Weger B B   Chakrabarti A A   Harms A C AC   Brennan L L   Hankemeier T T   Goulet L L   Konz T T   Martin F P FP   Moco S S   van der Greef J J  

Scientific reports 20181001 1


The menstrual cycle is an essential life rhythm governed by interacting levels of progesterone, estradiol, follicular stimulating, and luteinizing hormones. To study metabolic changes, biofluids were collected at four timepoints in the menstrual cycle from 34 healthy, premenopausal women. Serum hormones, urinary luteinizing hormone and self-reported menstrual cycle timing were used for a 5-phase cycle classification. Plasma and urine were analyzed using LC-MS and GC-MS for metabolomics and lipid  ...[more]

Similar Datasets

| S-EPMC4106219 | biostudies-literature
| S-EPMC4779110 | biostudies-literature
| S-EPMC4008697 | biostudies-literature
| S-EPMC8355156 | biostudies-literature
| S-EPMC2816193 | biostudies-other
| S-EPMC3055354 | biostudies-other
| S-EPMC7178826 | biostudies-literature
| S-EPMC5337441 | biostudies-literature
2023-09-06 | GSE234368 | GEO
| S-EPMC10709933 | biostudies-literature