Ontology highlight
ABSTRACT:
SUBMITTER: Vartak A
PROVIDER: S-EPMC6169316 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Vartak Abhishek A Hefny Fatma M FM Sucheck Steven J SJ
Organic letters 20171229 2
The synthesis of a trisaccharide (common to glycoform I and II) and a tetrasaccharide (common to glycoform I) from the outer core domain of Pseudomonas aeruginosa lipopolysaccharide (LPS) using a novel hydroquinone-based reducing-end capping group is reported. This multifunctional capping group was utilized as purification handle and was stable toward many common transformations in oligosaccharide synthesis. The access to outer-core LPS antigens with a TBDPS-protected hydroquinone (TPH) at the r ...[more]