Reversible Covalent End-Capping of Collagen Model Peptides.
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ABSTRACT:
SUBMITTER: Priem C
PROVIDER: S-EPMC6900188 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Publications
Reversible Covalent End-Capping of Collagen Model Peptides.
Priem Christoph C Geyer Armin A
Chemistry (Weinheim an der Bergstrasse, Germany) 20191017 63
The combination of supramolecular aggregation of collagen model peptides with reversible covalent end-capping of the formed triple helix in a single experimental set-up yielded minicollagens, which were characterized by a single melting temperature. In spite of the numerous possible reaction intermediates, a specific synthetic collagen with a leading, middle and trailing strand is formed in a highly cooperative self-assembly process. ...[more]
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