Ontology highlight
ABSTRACT:
SUBMITTER: Xu X
PROVIDER: S-EPMC6169480 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Xu Xusan X Liang Chunmei C Lv Dong D Yin Jingwen J Luo Xudong X Fu Jiawu J Yan Haifeng H Zhou Xia X Dai Zhun Z Zhu Dongjian D Xiong Susu S Lin Zhixiong Z Lin Juda J Zhao Bin B Li You Y Wang Yajun Y Ma Guoda G Li Keshen K
Frontiers in psychiatry 20180926
The <i>SAP97</i> gene is located in the schizophrenia susceptibility locus 3q29, and it encodes the synaptic scaffolding protein that interacts with the N-methyl-D-aspartate (NMDA) receptor, which is presumed to be dysregulated in schizophrenia. In this study, we genotyped a single-nucleotide polymorphism (SNP) (rs3915512) in the <i>SAP97</i> gene in 1114 patients with schizophrenia and 1036 healthy-matched controls in a Han Chinese population through the improved multiplex ligation detection re ...[more]