Ontology highlight
ABSTRACT:
SUBMITTER: Condorelli DF
PROVIDER: S-EPMC6172234 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Condorelli Daniele F DF Spampinato Giorgia G Valenti Giovanna G Musso Nicolò N Castorina Sergio S Barresi Vincenza V
Scientific reports 20181004 1
We re-examined the correlation between Broad Genomic Aberrations (BGAs) and transcriptomic profiles in Colorectal Cancer (CRC). Two types of BGAs have been examined: Broad Copy-Number Abnormal regions (BCNAs), distinguished in gain- and loss-type, and Copy-Neutral Loss of Heterozygosities (CNLOHs). Transcripts are classified as "OverT" or "UnderT" if overexpressed or underexpressed comparing CRCs bearing a specific BGA to CRCs not bearing it and as "UpT" or "DownT" if upregulated or downregulate ...[more]