Ontology highlight
ABSTRACT:
SUBMITTER: Stary J
PROVIDER: S-EPMC6173109 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Starý Jan J Zuna Jan J Zaliova Marketa M
F1000Research 20180928
Traditionally, genetic abnormalities detected by conventional karyotyping, fluorescence <i>in situ</i> hybridization, and polymerase chain reaction divided childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) into well-established genetic subtypes. This genetic classification has been prognostically relevant and thus used for the risk stratification of therapy. Recently, the introduction of genome-wide approaches, including massive parallel sequencing methods (whole-genome, -exome, ...[more]