Proteomics

Dataset Information

0

Proteogenomics of High hyperdiploid childhood acute lymphoblastic leukemia

ABSTRACT: Proteogenomic analysis and genomic profiling, RNA-sequencing, and mass spectrometry-based analysis of High hyperdiploid childhood acute lymphoblastic leukemia.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): B Cell, Bone Marrow, Blood

DISEASE(S): Acute Leukemia

SUBMITTER: Rozbeh Jafari  

LAB HEAD: Janne Lehtiö

PROVIDER: PXD010175 | Pride | 2019-02-25

REPOSITORIES: Pride

Json Xml

Dataset's files

Source:
Action DRS
ALL_hyperdiploid_peptide_table.txt Txt
ALL_hyperdiploid_protein_table.txt Txt
ALL_hyperdiploid_psm_table.txt Txt
MVKPLU_20160805_setA_IPG3-10_7of15ul_fr01.raw Raw
MVKPLU_20160805_setA_IPG3-10_7of15ul_fr02.raw Raw
Items per page:
1 - 5 of 220
altmetric image

Publications

Hyperdiploidy, i.e. gain of whole chromosomes, is one of the most common genetic features of childhood acute lymphoblastic leukemia (ALL), but its pathogenetic impact is poorly understood. Here, we report a proteogenomic analysis on matched datasets from genomic profiling, RNA-sequencing, and mass spectrometry-based analysis of >8,000 genes and proteins as well as Hi-C of primary patient samples from hyperdiploid and ETV6/RUNX1-positive pediatric ALL. We show that CTCF and cohesin, which are mas  ...[more]

Similar Datasets

Proteomics Proteogenomics of High hyperdiploid childhood acute lymphoblastic leukemia
2020-01-29 | MSV000084862 | MassIVE
Proteomics Proteomics analysis of childhood acute lymphoblastic leukemia cell lines reveals novel drug vulnerabilities
2022-03-26 | PXD023662 | Pride
Transcriptomics Transcriptome analysis of childhood acute lymphoblastic leukemia cell lines
2022-02-16 | GSE168386 | GEO
Methylation profiling Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia
2015-08-11 | GSE69229 | GEO
Genomics Tracking Therapy-Resistant Alterations in Childhood Acute Lymphoblastic Leukemia
| PRJNA1011437 | ENA
Genomics Tracking Therapy-Resistant Alterations in Childhood Acute Lymphoblastic Leukemia
| PRJNA1011438 | ENA
Genomics Transcriptome analysis of childhood acute lymphoblastic leukemia cell lines
| PRJNA707100 | ENA
Transcriptomics Germline genomic variations associated with childhood acute lymphoblastic leukemia
2009-08-16 | E-GEOD-17195 | biostudies-arrayexpress
Transcriptomics Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia
2015-08-11 | E-GEOD-69229 | biostudies-arrayexpress
Transcriptomics Gene Expression Profiling in T-ALL and B-ALL of Childhood Acute Lymphoblastic Leukemia
2012-08-03 | GSE39847 | GEO