Ontology highlight
ABSTRACT:
SUBMITTER: Mizukami T
PROVIDER: S-EPMC6173461 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Mizukami Tatsuzo T Kamachi Hirofumi H Fujii Yuki Y Matsuzawa Fumihiko F Einama Takahiro T Kawamata Futoshi F Kobayashi Nozomi N Hatanaka Yutaka Y Taketomi Akinobu A
Oncotarget 20180918 73
Pancreatic cancer often has a very poor prognosis, even after complete resection. The recurrence of hepatic and peritoneal metastases is an important prognostic factor; therefore, the development of improved adjuvant therapy is urgently required. Mesothelin is a cell surface glycoprotein whose expression is restricted to a variety of cancer types, including pancreatic cancer. This expression pattern makes mesothelin an attractive target for cancer therapy, and several agents targeting mesothelin ...[more]