Ontology highlight
ABSTRACT:
SUBMITTER: Pradhan-Sundd T
PROVIDER: S-EPMC6174089 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Pradhan-Sundd Tirthadipa T Vats Ravi R Russell Jacquelyn O JO Singh Sucha S Michael Adeola Adebayo AA Molina Laura L Kakar Shelly S Cornuet Pamela P Poddar Minakshi M Watkins Simon C SC Nejak-Bowen Kari N KN Monga Satdarshan P SP Sundd Prithu P
Gastroenterology 20180630 4
<h4>Background & aims</h4>Liver fibrosis, hepatocellular necrosis, inflammation, and proliferation of liver progenitor cells are features of chronic liver injury. Mouse models have been used to study the end-stage pathophysiology of chronic liver injury. However, little is known about differences in the mechanisms of liver injury among different mouse models because of our inability to visualize the progression of liver injury in vivo in mice. We developed a method to visualize bile transport an ...[more]