Ontology highlight
ABSTRACT:
SUBMITTER: Doot RK
PROVIDER: S-EPMC6174116 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Doot Robert K RK Dubroff Jacob G JG Scheuermann Joshua S JS Labban Kyle J KJ Cai Jenny J Hsieh Chia-Ju CJ Li Shihong S Lee Hsiaoju H Schubert Erin K EK Hou Catherine C Sheffer Regan R Schmitz Alexander A Xu Kuiying K Mach Robert H RH
EJNMMI physics 20181008 1
<h4>Background</h4>[<sup>18</sup>F]Fluortriopride (FTP) was developed as a dopamine D3-selective radiotracer, thought to be important to neurobiological reward pathways and implicated in drug addiction, Parkinson's disease, and schizophrenia. Preclinical radiation dosimetry studies found the gallbladder wall received the highest dose. A gallbladder dose reduction intervention was simulated using a novel reduction model for healthy adults following fatty-meal consumption. The goals of this study ...[more]