Ontology highlight
ABSTRACT:
SUBMITTER: Gnesin S
PROVIDER: S-EPMC7142191 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Gnesin Silvano S Müller Joachim J Burger Irene A IA Meisel Alexander A Siano Marco M Früh Martin M Choschzick Matthias M Müller Cristina C Schibli Roger R Ametamey Simon M SM Kaufmann Philipp A PA Treyer Valerie V Prior John O JO Schaefer Niklaus N
EJNMMI research 20200408 1
<h4>Background</h4>The folate receptor alpha (FRα) is an interesting target for imaging and therapy of different cancers. We present the first in-human radiation dosimetry and radiation safety results acquired within a prospective, multicentric trial (NCT03242993) evaluating the <sup>18</sup>F-AzaFol (3'-aza-2'-[<sup>18</sup>F]fluorofolic acid) as the first clinically assessed PET tracer targeting the FRα.<h4>Material and methods</h4>Six eligible patients presented a histologically confirmed ade ...[more]