Ontology highlight
ABSTRACT:
SUBMITTER: Bast BO
PROVIDER: S-EPMC6174543 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Bast Björn-Ole BO Rickert Uta U Schneppenheim Janna J Cossais François F Wilms Henrik H Arnold Philipp P Lucius Ralph R
Heliyon 20181003 10
Over the last years, studies on microglia cell function in chronic neuro-inflammation and neuronal necrosis pointed towards an eminent role of these cells in Multiple Sclerosis, Parkinson's and Alzheimer's Disease. It was found, that microglia cell activity can be stimulated towards a pro- or an anti-inflammatory profile, depending on the stimulating signals. Therefore, investigation of receptors expressed by microglia cells and ligands influencing their activation state is of eminent interest. ...[more]